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FDA sets May 2027 decision date on AMT-130 gene therapy for HD
4 min read
Latest News
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October 2026: This Month in Huntington’s Disease Research
4 min read
From sticky thoughts and pigs that model HD to DNA repair and promising drug trial results, October brought fresh insights into HD. Here’s what you might have missed!
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'Induced' stem cells make exciting advances
8 min read
Stem cells from HD patients: becoming important tools for researchers – and now correcting the HD mutation in the lab
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ASO gene silencing reaches further, lasts longer
7 min read
Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
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Phosphodiesterase inhibitors: new HD drugs entering trials soon
6 min read
CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.
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Interview: CHDI's scientific team
8 min read
HDBuzz interviews the top scientists from CHDI, the largest funder of Huntington's disease research in the world.
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Exercise increases cellular recycling
5 min read
Exercise boosts cellular recycling in mice. Could this be why exercise is also good for HD – or even help develop dru
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The HDBuzz Prize for young science writers
3 min read
Announcing the HDBuzz Prize for young science writers!
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What's the connection between Huntington's Disease and cancer?
6 min read
HD patients are less likely to get cancer, according to a study from Sweden – what does this mean?
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Closing the care gap: new guidelines for HD care
6 min read
Closing the care gap: new guidelines to help every Huntington's disease patient get great care
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Stem-cell neurons make the right connections
7 min read
Replacing neurons in mice with stem cells works much better than expected, suggesting that replacement therapy might
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2012 Therapeutics Conference: a retrospective
19 min read
HDBuzz looks back at the 2012 Huntington's Disease Therapeutics Conference
HDBuzz Trial Tracker
FDA accepts BLA for Priority Review, with a target decision date of 1 May 2027.
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
