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A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease
Latest News
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Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin
⏱️ 7 min read | A team of researchers developed a simple platform to test how toxic different types of HTT protein clumps are using a laboratory worm model. They showed that certain types of clumps are harmful to the worms, while others are not.
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New experiments clarify the role of SIRT1 in HD – or do they?
Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing
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Bone marrow transplantation in Huntington's Disease
Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target
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2011 – a year in Huntington's disease research
Looking back at a year in Huntington's disease research – and the first year of HDBuzz
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Gene therapy meets stem cells in liver disease success
Scientists combine gene therapy and stem cells to correct a genetic liver disease. Could this combo be retooled for H
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Chinese Huntington’s Disease Network launched
Chinese Huntington’s Disease Network launched. Good news for China, good news for the global HD community
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HDAC inhibitor drug protects memory in HD mice
CBP, a gene-switching protein, protects memory in HD mice; 'histone deacetylase inhibitor' drug mimics its effects
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Turning down the volume with dantrolene helps HD mice
Dantrolene, an muscle-relaxer drug already on the market, helps HD mice by reducing cellular calcium levels
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TRACK-HD reveals changes in HD mutation carriers, empowering future trials
Follow-up data from TRACK-HD study proves that we have the tests we need to successfully run drug trials for HD
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Huntexil hits the headlines again
Huntexil makes headlines with science journal article, but nothing's changed: another trial is needed before approval
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New antibody reveals dangerous parts of huntingtin protein
A new antibody lets scientists identify neurons that are going to die after producing mutant huntingtin
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
