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September 2025: This Month in Huntingtonâs Disease Research
Latest News
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KMO inhibitor drug improves lifespan of Huntington's disease mice
Positive results from tests of a new 'KMO inhibiting' drug in Huntington's disease mice
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Meet the enemy: neutron ray reveals HD protein structure
Scientists use beams of neutrons to study the structure of clumps of mutant huntingtin protein
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'Floating' gene-silencing drugs into the brain with exosomes
Exosomes â tiny bubbles made by cells â could be used to get gene silencing drugs from the bloodstream into the brain
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Improving Huntington's disease clinical trial recruitment through patient and family education
How can we improve recruitment into Huntington's disease clinical trials? Talking directly with families works!
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Chubby mice reveal the importance of the hypothalamus in Huntington's disease
Huntington's disease mice are fat but HD patients lose weight â is a brain area called the hypothalamus to blame?
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The genetic 'gray area' of Huntington's disease: what does it all mean?
Intermediate alleles and reduced penetrance â the genetic 'gray area' of Huntingtonâs disease, explained
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Dimebon fails in late-stage human HD clinical trial
Dimebon fails to improve symptoms in HD patients in the HORIZON trial
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FDA: further trial needed for Huntexil approval in HD
Bad news for Huntexil â the FDA requires another trial before it can be approved in the US
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Successful gene therapy trial in Parkinsonâs Disease gives hope for HD
Success for brain âgene therapyâ in Parkinsonâs disease â good news for similar treatments being developed in HD
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Gene silencing for HD: the story so far
Is gene silencing as exciting as it sounds for HD, and what might the future hold?