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FDA sets May 2027 decision date on AMT-130 gene therapy for HD
4 min read
Latest News
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Prana announces results of Reach2HD trial of PBT2 for Huntington's disease
12 min read
Results are in for a clinical trial testing the drug PBT2 for HD. Are the claims in the announcement justified?
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Does high-dose creatine "slow the onset" of Huntington's Disease?
7 min read
A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?
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Joint HDBuzz Prizewinner: Yeast studies suggest a new way to protect cells from 'oxidative damage'
7 min read
Researchers identify Gpx1, a protein that may be protective in HD. An existing drug can mimic its antioxidant effect.
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Joint HDBuzz Prizewinner: Pennies for your neurons — copper’s bad influence on Huntington’s disease
7 min read
There is copper in your brain! Check out how copper and the Huntington’s disease protein are partners in crime.
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Could a 'brain shuttle' get Huntington's disease drugs to where they're needed?
5 min read
Roche's 'brain shuttle' sneaks drugs past the blood-brain barrier. Could it work for HD gene silencing drugs?
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Is a new Huntington’s Disease drug study on the right Trk?
7 min read
A recent HD animal study reveals that a small molecule drug could be an effective “Trk” to target for HD therapeutics
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DNA shutdown proteins in Huntington's disease: More than meets the eye
6 min read
Blocking HDAC4 improves Huntington's disease-related problems in cells and mice – but in a surprising way
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More evidence points to Huntington's disease exercise benefit
6 min read
Two studies show exercise benefits for some symptoms of Huntington's disease. Just don't believe everything you read.
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Do dairy foods accelerate Huntington's disease?
6 min read
Is there a link between consuming dairy food and earlier onset in people with the Huntington's disease mutation?
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Could a new "jaw-dropping" breakthrough help treat Huntington's Disease?
8 min read
The news has recently been full of stories about CRISPR, a new "jaw-dropping" DNA-editing technology. Hype or hope?
HDBuzz Trial Tracker
FDA accepts BLA for Priority Review, with a target decision date of 1 May 2027.
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
