Latest News
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Gene silencing drug safe in ALS patients… bring on Huntington's disease trials
Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.
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A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene
DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD
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Landmark study puts Huntington's disease trials on TRACK
Final results from the TRACK-HD study show very specific changes in HD. We're ready for trials: bring on the drugs!
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Splicing with danger: a new way of thinking about the harmful Huntington's disease protein
Researchers discover a new way harmful fragments of the huntingtin protein are made in neurons.
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Proposed Huntington's disease 'biomarker' is not useful, new study suggests
New study shows a blood chemical called '8OHdG' is not a good biomarker for HD. Bad news?
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Is access to predictive genetic testing for Huntington's disease a problem?
Is access to predictive genetic testing for Huntington's disease a problem? A UBC study says it is.
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HD Therapeutics Conference 2013 Updates: Day 3
Final day of our coverage of the Huntington's Disease Therapeutics Conference 2013
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HD Therapeutics Conference 2013 Updates: Day 2
Day 2 of our coverage of the Huntington's Disease Therapeutics Conference
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Major Roche-Isis deal boosts Huntington's disease gene silencing
'ASO' gene silencing drugs for HD boosted by major deal between Isis Pharmaceuticals and Roche
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HD Therapeutics Conference 2013 Updates: Day 1
Day 1 of our coverage of the Huntington's Disease Therapeutics Conference
HDBuzz Trial Tracker
Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
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REGEN4HD, Phase 1 stem cell implantation study commences
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Looking back and moving forward: Questions and lessons 4 weeks out from Roche’s disappointing news
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July 2026: This Month in Huntington’s Disease Research
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Putting it in print: a clinical trial trying to rein in runaway pruning
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Joining the Starting Lineup: MutLβ’s Role in DNA Repeat Expansions
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Catching a Giant Protein: Five New Ways to Grab Huntingtin
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