Latest News
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Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis
⏱️ 4 min read
CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit
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Should we worry about a huntingtin invasion?
⏱️ 5 min read
Cool lab experiments show the huntington's disease protein jumping between cells. Does this matter for HD patients?
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EuroBuzz 2014 Video, day one
⏱️ 13 min read
Video of our first live session at the European Huntington's Disease Network Meeting.
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EuroBuzz 2014 Video, day two
⏱️ 21 min read
Video of our second live session at the European Huntington's Disease Network Meeting.
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Melatonin alterations in Huntington's disease help explain trouble with sleep
⏱️ 7 min read
Study shows HD patients have decreased levels of melatonin, which may explain why so many suffer from sleep problems
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EuroBuzz 2014: day three
⏱️ 4 min read
Our third and final report on the 2014 European Huntington's Disease Network meeting in Barcelona
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EuroBuzz 2014: day two
⏱️ 7 min read
HDBuzz reports on the second day of science at the European HD Network meeting in Barcelona
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EuroBuzz 2014: day one
⏱️ 11 min read
Highlights from the opening day of the 2014 European Huntington's Disease network in Barcelona, Spain
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Going toe-to-toe with tau: new insights into the chemical basis of Huntington’s disease
⏱️ 6 min read
Does tau protein – which causes problems in other neurodegenerative diseases – contribute to Huntington's disease?
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New results bring BDNF therapies into focus
⏱️ 7 min read
Some unexpected findings suggest new ways to aim at an old target in HD
HDBuzz Trial Tracker
FDA accepts BLA for Priority Review, with a target decision date of 1 May 2027.
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Updates from the ongoing Phase 3 INVEST-HD trial of votoplam
Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01
Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515
Previously featured
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EHDN 2026 Part 1: What’s next in the Huntington’s disease treatment pipeline?
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Skyhawk’s drug trial takes flight in the US
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FDA sets May 2027 decision date on AMT-130 gene therapy for HD
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October 2026: This Month in Huntington’s Disease Research
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Turning down huntingtin: Alnylam’s brezosiran shows promising early result
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