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AMT-130 at Four Years: Hopeful Signs, Complex Controls
Latest News
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September 2026: This month in Huntington’s disease research
September brought progress across the HD research landscape. From brain waves and visual thinking to DNA repeats, nutrition, inclusive care, new technologies, and encouraging SKY-0515 data, we round up a busy month in Huntington’s disease research.
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New collaboration seeks to speed Huntington's disease drug licensing
Critical Path Institute launches new initiative to get HD drugs licensed as quickly as possible
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HDSA’s Q&A on the latest huntingtin-lowering update from Ionis and Roche
Our friends at @hdsa have produced this really good Q&A document about the latest huntingtin-lowering news.
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Exciting Experiments in "Open Science" by Huntington's Researchers
Brave scientists open their notebooks to help drive HD research at the risk of getting "scooped".
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The structure of the protein that causes Huntington's disease, revealed
Huntingtin protein's structure is now clear thanks to cryo-electron microscopy. This is kind of a big deal
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Huntington's disease therapeutics conference 2018 – day 3
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein – and lowering it
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Huntington's disease therapeutics conference 2018 – day 2
DNA takes centre stage for day 2 of the Huntington's Disease Therapeutics Conference in Palm Springs
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Huntington's disease therapeutics conference 2018 – day 1
Our daily roundup of the science presented at the 2018 HD Therapeutics Conference in Palm Springs
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An early role for the Huntington's disease gene – but don't believe all the headlines
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
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New interest in an old target
Promising results in mice provide renewed optimism for mGluR5 antagonists
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Ask the expert: Q&A on the huntingtin-lowering trial program
In a Q&A coordinated by the UK HD Association, Dr Ed Wild answers questions on the recently-announced trial
HDBuzz Trial Tracker
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Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
REGEN4HD, Phase 1 stem cell implantation study commences
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
