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Your DNA Shouldn’t Cost You Your Insurance: What HD Families Need to Know
Latest News
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2024 HDBuzz Prize: A NEAT new dance partner for Huntingtin
We’re proud to announce AJ Keefe as our last HDBuzz Prize winner of 2024! Our cells are an intricate choreography between various molecular dancers. Knowing who moves well with whom, and how that changes with disease, could help advance drugs for HD.
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Beta-blockers associated with delayed onset and decreased progression of Huntington’s disease
A well-studied, widely used class of drugs for heart health may have benefits for Huntington’s disease. A new paper associated beta-blocker use with delayed onset and slower disease progression. Should you ask your doctor for a new prescription?
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Moving into the Fast Lane: uniQure and the FDA Are on the Same Track for Accelerated Approval
In an update shared today, uniQure announced alignment with the US drug regulator on key criteria for accelerated approval of drugs for Huntington’s disease.
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Interim update from Vico Therapeutics on their CAG-targeting drug, VO659
Vico Therapeutics have shared interim data about their drug, VO659, which targets the CAG expansion that causes several genetic diseases, including #Huntingtonsdisease and #spinocerebellarataxia
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Going boldly: First person treated in Phase 1 clinical trial by Alnylam Pharmaceuticals
A new Phase 1 clinical trial for the huntingtin-lowering drug ALN-HTT02 was initiated this week with the first dose given. Read on to learn details about the trial and how it compares to other ongoing huntingtin-lowering trials in the clinic.
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Giving Thanks to the Huntington's Disease Family Community for Advancing Research
At this time of giving, we want to give thanks to you, the Huntington’s disease (HD) community, for all you have done for HD research, bringing us closer to medicines which will one day slow or halt HD.
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Self-determination on the HD journey: the role of Advanced Care Planning
Advanced Care Planning is a tool that can allow people living with Huntington’s disease to compassionately engage with loved ones about their future care, taking thoughtful steps at their own pace while they’re able, to ensure their wishes are met.
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2024 HDBuzz Prize: Beyond nerve cells – who are the other players in the HD brain?
We're proud to announce Jenny Lange as a 2024 HDBuzz Prize winner! Our brains are made up of many types of cells that play different roles in the changes caused by HD. This study dives into a star-shaped cell called astrocytes and their role in HD.
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Face-to-face: Huntington’s disease families are heard by the FDA
The HDSA recently coordinated a meeting between Huntington’s disease families and the US regulatory agency that approves medicines, to amplify the community’s voice and help move us toward treatments.
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The dust has settled: Sage’s dalzanemdor won’t advance for cognitive impairment
Changes in thinking, learning, and memory are some of the most distressing and impactful in Huntington’s disease. Sage Therapeutics was advancing their drug dalzanemdor to treat these symptoms, but unfortunately this program will be halted.
HDBuzz Trial Tracker
Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
REGEN4HD, Phase 1 stem cell implantation study commences
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
