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DNA Repair in Huntingtonās Disease: Not Up to Par?
Latest News
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Unlocking the Mindās Eye: How Huntingtonās Disease Changes How We See and Process the World
For many with Huntingtonās disease, recognising faces, navigating familiar places, or reading can be difficult. Scientists studied how and when HD affects how the brain processes what we seeācrucial research to improve support for people with HD.
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Fountain of youth: HTT protein repairs neurons by maintaining youthful state
Another clue about the normal function of the huntingtin protein; a team of scientists has recently found that huntingtin seems to play an important role in repairing damaged nerve cells
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What does COVID-19 mean for Huntingtonās disease families and HD research?
COVID-19 update: what does it mean for HD families, how does it impact HD research, and how has it changed the way science works?
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New molecule can reverse the Huntington's disease mutation in lab models
A collaborative team of scientists from Canada and Japan have identified a small molecule which can change the CAG-repeat length in different lab models of Huntington's disease. #HuntingtonsDisease #DrugDiscovery
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Huntingtonās disease therapeutics conference 2020 – Day 3
HDBuzz reports from the annual Huntingtonās disease therapeutics conference in Palm Springs
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Huntingtonās disease therapeutics conference 2020 – Day 2
HDBuzz reports from the annual Huntingtonās disease therapeutics conference in Palm Springs
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Huntingtonās disease therapeutics conference 2020 – Day 1
HDBuzz reports from the annual Huntingtonās disease therapeutics conference in Palm Springs
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Screening the entire genome for new drug targets for HD
Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers
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The third dimension: using minibrains to understand brain development changes in HD
Researchers show that highly expanded CAGs in the HD gene can cause early developmental changes using 3D brain models called organoids. Whatād they find?
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Unpacking Wave's PRECISION-HD2 huntingtin-lowering trial announcement
Wave Life Sciences announces that its antisense drug WVE-120102 has lowered mutant huntingtin protein in cerebrospinal fluid, but investors seem disappointed. Rather confusing ā what do we know for sure?
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Could molecular handcuffs lower the protein that causes Huntington's disease?
Researchers got surprisingly lucky when looking for drug molecules to pull mutant huntingtin protein into a cellular garbage disposal machine