synapses
-
Putting it in print: a clinical trial trying to rein in runaway pruning
⏱️10 min read | Four years after announcing positive results in their trial of ANX005 (tanruprubart) for HD, Annexon has formally published the results. It’s safe, hits its target, and may have helped some participants – so what’s the holdup?
By Dr Leora Fox -
HD and Histamines: Targeting Hybrid Receptors to Quiet Stressful Brain Talk
Scientists recently used an antihistamine to quiet dopamine messages in the brain and treat HD-like symptoms in mice. But beware the hype suggesting that allergy medicines could be used to slow down HD.
By Dr Leora Fox -
New results bring BDNF therapies into focus
Some unexpected findings suggest new ways to aim at an old target in HD
-
HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease
Recent study in fruit flies identifies a new connection between synapses and HD