metabolism
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Screening the entire genome for new drug targets for HD
Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers
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Sheep leading the flock: metabolism and biomarkers in HD
Sheep can help us to identify HD biomarkers and recognize metabolic changes that occur before symptoms develop.
By Dr Leora Fox -
Through a Broader Lens: Looking at Non-Motor Symptoms in HD
Sleep deficits precede motor problems in HD
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mTORC1 tips the scales in Huntington’s disease mice
Weighing the scales on mTORC1: A possible new target for HD therapeutics?
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Can this synthetic oil help feed the brain in Huntington's disease?
A new study shows a synthetic oil called triheptanoin changes how HD brains use energy. But will it help HD?
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Largest creatine clinical trial for Huntington's disease halted after 'futility' analysis
CREST-E, a trial of the supplement creatine, has been stopped after an early analysis found it couldn't show benefit
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2CARE study of coenzyme Q for Huntington's disease ends in disappointment
The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?
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Does high-dose creatine "slow the onset" of Huntington's Disease?
A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?
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The sweet lowdown: Huntington's disease brains use sugar differently
New observations suggest that the brains of HD mutation carriers consume energy differently. Do we care? (Yes!)
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Liver changes in Huntington's disease patients suggest more 'whole body' research needed
A new study suggests that liver changes may occur in HD patients, opening up new avenues of research