huntingtin-function
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Huntington's disease therapeutics conference 2019 – Day 3
12 min read
New insights into the huntingtin protein, and further progress in turning genetic quirks that modify the course of HD into treatments, on the final day of the therapeutics conference
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Huntington's disease therapeutics conference 2018 – day 3
14 min read
Updates from day 3 of the Huntington’s Disease Therapeutics Conference: huntingtin protein – and lowering it
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An early role for the Huntington's disease gene – but don't believe all the headlines
13 min read
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
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New roles for huntingtin: removing a healthy protein to understand its function
7 min read
Completely removing normal huntingtin in adults may disrupt healthy brain function, a recent study suggests.
By Dr Leora Fox -
Huntington's Disease Therapeutics Conference 2017 – Day 1
6 min read
HDBuzz summarises all the science from the 2017 Huntington's Disease Therapeutics Conference in Malta – day 1
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Enemy at the gates – huntingtin disrupts nuclear transport
7 min read
Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.
By Tom Peskett -
Huntingtin grabs a hammer: DNA repair in HD
8 min read
Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.
By Dr Leora Fox -
The benefits of migration, highlighted in Huntington's disease
6 min read
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
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A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?
7 min read
What if some problems in HD were due to something other than a harmful protein?
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Ultra-rare mutations highlight the importance of the HD gene in brain development
8 min read
New technology enables researchers to find ultra-rare mutations in the HD gene, distinct from the one causing HD
By Megan Krench