disease-modifying
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Prana Biotech's new trial of PBT2 in Huntington's disease: the lowdown
Prana Biotech's PBT2 trial in Huntington's disease: what we know so far & what copper has to do with the mutant prote
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Protein-folding drug helps HD mice… for a while
A drug that activates an ancient cellular defense mechanism slows down HD in mice – but why didn’t the benefit last?
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Re-routing the huntingtin protein inside cells
Canadian team decodes the tags that re-route the huntingtin protein within cells, helping explain how it becomes toxi
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KMO inhibitor drug improves lifespan of Huntington's disease mice
Positive results from tests of a new 'KMO inhibiting' drug in Huntington's disease mice
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Gene silencing for HD: the story so far
Is gene silencing as exciting as it sounds for HD, and what might the future hold?
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Interview: Graeme Bilbe, Global Head for Neuroscience at Novartis
HDBuzz interviews Graeme Bilbe, Global Head for Neuroscience at pharmaceutical giant Novartis, about their HD researc
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CHDI Report: Day 3
Day 3 of CHDI’s HD therapeutics conference: growth factors and CHDI’s advanced therapies
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CHDI Report: Day 2
Day 2 of CHDI’s HD therapeutics conference: figuring out energy problems in HD
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CHDI Report: Day 1
Day 1 of CHDI’s HD therapeutics conference: exploring abnormal brain connections and silencing the HD gene
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Anti-nausea drug helps cells with the HD mutation stay healthy in a surprising way
Anti-nausea drug meclizine protects cells with the HD mutation from death by reducing cellular energy production