disease-modifying – Page 2

Measuring harmful huntingtin protein in the brain’s bath water

How will we know whether HD-lowering treatments are working? New advancements in the detection of mutant huntingtin.

May 18, 2015

Does a specific amino acid deficiency contribute to the development of HD?

April 21, 2014

A new study claims that high-dose creatine "slows the onset of Huntington Disease". How much hope and how much hype?

February 11, 2014

Prana Biotechnology has released data demonstrating their drug, PBT2, is effective in animal models of HD

January 14, 2013

Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?

June 21, 2012

2 bits of good news for RNAi gene silencing in HD: it's safe over six months, and a way to treat bigger brain areas

January 24, 2012

Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing

January 12, 2012

Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target

January 4, 2012

Melatonin delays disease onset and extends survival in Huntington's disease mice – could it do the same for patients?

October 31, 2011

HDAC inhibitors explained, plus how new HDAC-related Huntington's disease research might help us find biomarkers

October 14, 2011