crispr
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Molecular Surgeons for Huntingtonâs Disease Catch a RIDE with CRISPR Advancements
A new CRISPR-based technology, called RIDE, is a leap forward for this trail-blazing technology. With the precision of a scalpel sharp enough to rewrite the very code of life, researchers have used it with the hope of treating Huntingtonâs disease.
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CRISPR-based drugs: one giant leap for mankind
Casgevy is the first CRISPR-based drug to make its way through the approval process, all but curing Sickle Cell Disease and itâs paving the way for similar drugs targeting other diseases. Is Huntingtonâs disease next?
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Another tool in the box: Creation of a molecular âdimmer switchâ advances gene editing
A new system has been developed that allows researchers to fine-tune gene expression with oral drugs, work that provides a powerful tool for gene editing.
By Dr Leora Fox -
Does blood hold the key to testing treatments earlier in HD patients?
A new study by researchers at Johns Hopkins describes a non-invasive way to track progression of Huntingtonâs disease. This could be used before patients even start showing symptoms to help test treatments in early stages of disease.
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A first for CRISPR gene editing could have wider applications for human disease
A successful early trial of a drug for Familial Transthyretic Amyloidosis showed that CRISPR gene editing could be safely used in the human body. What does this mean for gene editing in HD?
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Caution urged for the use of gene-editing technology CRISPR
A recent series of studies on the gene-editing method CRISPR have raised concerns about the suitability of this technology for the treatment of genetic illnesses such as Huntington's disease
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Screening the entire genome for new drug targets for HD
Scientists screen the ENTIRE genome to find new potential therapeutic targets for HD. This ambitious study provides a wealth of data for HD researchers
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First Dolly, now Piglet; a new Huntingtonâs disease pig knock-in model confirmed
For the first time in HD research, an animal model has been created in pigs using 2 cutting edge DNA editing t
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An early role for the Huntington's disease gene â but don't believe all the headlines
A surprising new paper sheds light on the role of the HD gene early in development. Should we worry?
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Switch off the genome editor when youâre done
CRISPR genome editing just got an off-switch. We cut through the hype to explore the technology in HD