brain-connections
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Your Voice Matters: Using Speech to Monitor Huntington’s Disease
9 min read
HD researchers developed an AI-powered tool that analyzes a short counting task. Its speech measures reflected clinical scores and HD-related changes over time, suggesting it could be used as a remote monitoring tool in future.
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A Fault In The Supercomputer
8 min read
Your brain is an advanced supercomputer. But in HD, a core processor starts to malfunction. A research group at UCLA has taken a close look to visualize the specific circuits going haywire – and how they look different in HD.
By Dr Chris Kay -
2025 HDBuzz Prize: Calm Before the Storm: Early Clues of Huntington’s Disease Found in Brainwaves
7 min read
We’re proud to announce Eva Woods as a 2025 HDBuzz Prize winner! Scientists spotted small brainwave changes in people with HD before symptoms begin. These early electrical “whispers” of HD could help track effects years before diagnosis.
By Eva Woods -
When the Brain’s Orchestra Falls Out of Tune: A New Map of Huntington’s Disease Progression
7 min read
New research maps Huntington’s disease progression like a symphony unraveling. The brain first overcommunicates, then loses sync, and finally falls silent, each stage driven by different biological mechanisms.
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One Disease, Many Paths: How Brain Wiring Shapes Huntington’s Symptoms
7 min read
HD starts with a single gene change, but its effects travel many roads. New work shows how brain networks breakdown or reroute. Whether movement, thinking, or mood are most affected, we may be able to guide care in a more personalized direction.
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Mini brains grown in a dish shed light on Huntington’s disease and how we might treat it
7 min read
Exciting new findings using 3D human lab-grown mini brains inform ongoing HTT-lowering trials and suggest that stem cell transplants for HD may improve cell-to-cell communication and reduce disease features.
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Huntington's disease therapeutics conference 2018 – day 1
7 min read
Our daily roundup of the science presented at the 2018 HD Therapeutics Conference in Palm Springs
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Huntington's Disease Therapeutics Conference 2017 – Day 3
5 min read
HDBuzz summarises final day of the 2017 Huntington's Disease Therapeutics Conference in Malta
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The benefits of migration, highlighted in Huntington's disease
6 min read
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
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Mapping the anatomy of HD: a whole-brain history
10 min read
A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.
By Dr Leora Fox