brain-connections
-
One Disease, Many Paths: How Brain Wiring Shapes Huntington’s Symptoms
HD starts with a single gene change, but its effects travel many roads. New work shows how brain networks breakdown or reroute. Whether movement, thinking, or mood are most affected, we may be able to guide care in a more personalized direction.
-
Mini brains grown in a dish shed light on Huntington’s disease and how we might treat it
Exciting new findings using 3D human lab-grown mini brains inform ongoing HTT-lowering trials and suggest that stem cell transplants for HD may improve cell-to-cell communication and reduce disease features.
-
Huntington's disease therapeutics conference 2018 – day 1
Our daily roundup of the science presented at the 2018 HD Therapeutics Conference in Palm Springs
-
Huntington's Disease Therapeutics Conference 2017 – Day 3
HDBuzz summarises final day of the 2017 Huntington's Disease Therapeutics Conference in Malta
-
The benefits of migration, highlighted in Huntington's disease
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
-
Mapping the anatomy of HD: a whole-brain history
A new book for researchers describes a century of HD anatomy and presents evidence that HD affects the whole brain.
By Dr Leora Fox -
Turning skin cells into brain cells: a Huntington's disease research breakthrough?
Scientists can now change human skin cells into working neurons, like the ones that are most affected in HD.
-
The brain in Huntington's disease: greater than the sum of its parts?
An important new study asks the question: what parts of the brain might need most help in HD?