biomarkers
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Your Voice Matters: Using Speech to Monitor Huntington’s Disease
9 min read
HD researchers developed an AI-powered tool that analyzes a short counting task. Its speech measures reflected clinical scores and HD-related changes over time, suggesting it could be used as a remote monitoring tool in future.
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Could Brain Waves Help Track Huntington’s Disease?
7 min read
A review of 23 studies found that EEG changes were linked to disease progression and clinical measures in HD. While more research is needed, EEG holds potential to become a simple, non-invasive biomarker for monitoring HD over time.
By Dr Laura Ohl -
A Window into the Eyes: Using Ocular Biomarkers to Track Progression in Huntington’s Disease
6 min read
A new review from the University of Cambridge explores ocular biomarkers in HD, including retinal scans and eye movement tracking.
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City Under the Microscope: How Two Proteins Could Help Track Huntington’s Disease
9 min read
In Huntington’s disease research, biomarkers are the secret weapon for spotting treatment effects. A new blood study uncovers two proteins, CAP1 and CAPZB, that, with additional work, could help track the disease before symptoms begin.
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Listening for Whispers: How a Tiny Protein Could Transform HD Research
6 min read
A 14-year study tracking NfL levels in people with the HD gene shows this tiny protein can signal disease progression many years before symptoms start. The longest follow-up study yet adds weight to NfL as a powerful tool for HD research.
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Huntington’s Disease Clinical Expert Prof. Ed Wild Shares Hopeful View For 2025
20 min read
The HDBuzz team caught up with editor emeritus and Huntington's disease specialist, Prof Ed Wild to hear his thoughts on what 2025 has in store for the Huntington's disease community
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Spotting HD Early: The Clues Hidden in Young Brains
11 min read
Researchers have detected early changes in brain scans and biomarkers in young people with the Huntington’s disease gene, 20 years before symptoms are predicted to appear. These findings could help develop medicines to treat HD earlier in life.
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2024: Year in Review
17 min read
As we begin 2025, we look back on all of the Huntington’s disease research news and progress the field has made in the last 12 months.
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Cry your eyes out: detecting huntingtin in tears
5 min read
Is someone cutting onions? Expanded huntingtin can now be detected in tears to help scientists track disease progression.
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Huntington’s disease therapeutics conference 2023 – Day 3
18 min read
Check out research updates from Day 3 of the 2022 HD Therapeutics Conference #HDTC2023