Latest News
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Chubby mice reveal the importance of the hypothalamus in Huntington's disease
Huntington's disease mice are fat but HD patients lose weight – is a brain area called the hypothalamus to blame?
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The genetic 'gray area' of Huntington's disease: what does it all mean?
Intermediate alleles and reduced penetrance – the genetic 'gray area' of Huntington’s disease, explained
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Dimebon fails in late-stage human HD clinical trial
Dimebon fails to improve symptoms in HD patients in the HORIZON trial
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FDA: further trial needed for Huntexil approval in HD
Bad news for Huntexil – the FDA requires another trial before it can be approved in the US
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Successful gene therapy trial in Parkinson’s Disease gives hope for HD
Success for brain ‘gene therapy’ in Parkinson’s disease – good news for similar treatments being developed in HD
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Gene silencing for HD: the story so far
Is gene silencing as exciting as it sounds for HD, and what might the future hold?
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Interview: Graeme Bilbe, Global Head for Neuroscience at Novartis
HDBuzz interviews Graeme Bilbe, Global Head for Neuroscience at pharmaceutical giant Novartis, about their HD researc
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What do sheep brains have to do with HD?
How smart are sheep, and why do HD researchers care?
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Interview: CHDI Management
HDBuzz interviews three top scientists from CHDI, the biggest funder and driver of HD research worldwide
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CHDI Report: Day 3
Day 3 of CHDI’s HD therapeutics conference: growth factors and CHDI’s advanced therapies
HDBuzz Trial Tracker
Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Blocking a toxic fragment: new mouse study highlights the importance of HTT1a in Huntington’s disease
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Between Care, Genes, and Systems: Navigating Huntington’s Disease as a Caregiver
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Your Wrist on Watch: Could a Smartwatch Reveal Huntington’s Disease Symptoms?
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March 2026: This Month in Huntington’s Disease Research
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Two Heads Are Better Than One: Combined Physical and Music Therapy for Late-Stage Huntington’s Disease
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