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  • First participant dosed in pioneering neural stem cell trial for Huntington’s disease

    First participant dosed in pioneering neural stem cell trial for Huntington’s disease

Latest News

HDBuzz Trial Tracker

Expected submission for regulatory approval of AMT-130 in the UK

uniQure
Expected: Q3 2026

Type B Meeting with FDA to Discuss Study Design Approaches for AMT-130

uniQure
Expected: Q2 2026

Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.

Novartis/PTC Therapeutics
Expected: Spring 2026

REGEN4HD, Phase 1 stem cell implantation study commences

University of California, Irvine
Expected: Not disclosed

Phase 3 for SOM3355 to commence

SOM Biotech
Expected: Q4 2026

GENERATION-HD2 Trial Expected to Complete

Roche
Expected: 2026

Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02

Alnylam Pharmaceuticals
Expected: 2026

Update on Planned Phase 2/3 Study for WVE-003

Wave Life Sciences
Expected: Not disclosed

Update on Phase 1/2a Clinical Data of VO659

Vico Therapeutics
Expected: Not disclosed

First participant in Phase 1/2 gene therapy trial dosed

Roche
Expected: Not disclosed

First participant dosed in POINT-HD trial

Roche
Expected: Not disclosed

Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial

Skyhawk Therapeutics
Expected: Not disclosed

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