HDBuzz – Page 46 – Huntington’s disease research news.

Huntington’s disease research news.

In plain language. Written by scientists.
For the global HD community.

Could rewiring the brain’s “brakes” improve movement in Huntington’s disease?

6 min read
October 12, 2026

Latest News

Gene silencing drug safe in ALS patients… bring on Huntington's disease trials

7 min read
Gene silencing drug injected into spinal fluid in ALS patients proves safe. Good news for similar planned HD trials.

June 29, 2013
A DNA repair protein modifies the stability of long CAG tracts in the Huntington's disease gene

9 min read
DNA repair is a critical process to cells, but errors in this process might explain 'repeat instability' in HD

June 3, 2013
Landmark study puts Huntington's disease trials on TRACK

7 min read
Final results from the TRACK-HD study show very specific changes in HD. We're ready for trials: bring on the drugs!

May 9, 2013
Splicing with danger: a new way of thinking about the harmful Huntington's disease protein

6 min read
Researchers discover a new way harmful fragments of the huntingtin protein are made in neurons.

May 6, 2013
Proposed Huntington's disease 'biomarker' is not useful, new study suggests

7 min read
New study shows a blood chemical called '8OHdG' is not a good biomarker for HD. Bad news?

April 25, 2013
Is access to predictive genetic testing for Huntington's disease a problem?

6 min read
Is access to predictive genetic testing for Huntington's disease a problem? A UBC study says it is.

April 23, 2013
HD Therapeutics Conference 2013 Updates: Day 3

9 min read
Final day of our coverage of the Huntington's Disease Therapeutics Conference 2013

April 11, 2013
HD Therapeutics Conference 2013 Updates: Day 2

6 min read
Day 2 of our coverage of the Huntington's Disease Therapeutics Conference

April 10, 2013
Major Roche-Isis deal boosts Huntington's disease gene silencing

5 min read
'ASO' gene silencing drugs for HD boosted by major deal between Isis Pharmaceuticals and Roche

April 9, 2013
HD Therapeutics Conference 2013 Updates: Day 1

5 min read
Day 1 of our coverage of the Huntington's Disease Therapeutics Conference

April 9, 2013

HDBuzz Trial Tracker

Initial Phase 1 clinical data from ALN-HTT02

Alnylam Pharmaceuticals

Expected: Q4 2026

Phase 3 trial of SOM3355 expected to begin

SOM Biotech

Expected: Q4 2026

Regulatory updates on AMT-130 following US and UK submissions

uniQure

Expected: Not disclosed

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Update on plans for a Phase 2/3 study of WVE-003

Wave Life Sciences

Expected: Not disclosed

PRECISE-HD Phase 3 trial of pridopidine begins recruitment

Prilenia-Ferrer

Expected: N/A

Updates from the ongoing Phase 3 INVEST-HD trial of votoplam

Novartis/PTC Therapeutics

Expected: Not disclosed

Updates from the Phase 1b/2a REGEN4HD trial of neural stem cell therapy hNSC-01

University of California, Irvine

Expected: Not disclosed

Further update from the Phase 1/2a trial of VO659

Vico Therapeutics

Expected: Not disclosed

Updates from the Phase 1/2 trial of RG6662 (SPK-10001) gene therapy

Roche

Expected: Not disclosed

Updates from the ongoing Phase 2/3 FALCON-HD trial of SKY-0515

Skyhawk Therapeutics

Expected: Not disclosed

Updates from the Phase 1 INSIGHTT trial of SRP-1005

Sarepta Therapeutics

Expected: Not disclosed

Previously featured

Your Voice Matters: Using Speech to Monitor Huntington’s Disease

October 8, 2026
Can’t Get You Out of My Head: The Huntington’s Disease Symptom That’s More Than Just Repetition

October 5, 2026
AMT-130 at Four Years: Hopeful Signs, Complex Controls

September 30, 2026
September 2026: This month in Huntington’s disease research

September 28, 2026
Studying Stutters: What 900,000 genomes teach us about growing DNA repeats

September 24, 2026

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