Latest News
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Turning down the volume with dantrolene helps HD mice
Dantrolene, an muscle-relaxer drug already on the market, helps HD mice by reducing cellular calcium levels
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TRACK-HD reveals changes in HD mutation carriers, empowering future trials
Follow-up data from TRACK-HD study proves that we have the tests we need to successfully run drug trials for HD
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Huntexil hits the headlines again
Huntexil makes headlines with science journal article, but nothing's changed: another trial is needed before approval
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New antibody reveals dangerous parts of huntingtin protein
A new antibody lets scientists identify neurons that are going to die after producing mutant huntingtin
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Safety trials add crucial piece to gene silencing jigsaw
Three trials of drugs to 'silence' the HD gene in monkeys show they hit the target safely. Human trials coming soon.
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Melatonin treatment success in HD mice
Melatonin delays disease onset and extends survival in Huntington's disease mice – could it do the same for patients?
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HD World Congress 2011: a retrospective
HDBuzz looks back at the highlights of the Huntington's disease world congress 2011 in Melbourne
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HDAC inhibitors and a possible 'blood biomarker'
HDAC inhibitors explained, plus how new HDAC-related Huntington's disease research might help us find biomarkers
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HD just got cilia
Huntington's disease just got cilia: huntingtin protein affects tiny but important hairs on cells called cilia
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Gene silencing takes a targeted step forward
Targeting the mutant Huntington's disease gene for silencing, while leaving the healthy gene untouched
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Split Between Two Worlds: The Psychological Challenges for People at Risk of Huntington’s Disease
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Putting it in print: oral drug branaplam lowered huntingtin, but safety concerns halted development
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A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease
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Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin
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January 2026: This Month in Huntington’s Disease Research
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