Latest News
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Double success for huntingtin RNAi gene silencing
2 bits of good news for RNAi gene silencing in HD: it's safe over six months, and a way to treat bigger brain areas
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New experiments clarify the role of SIRT1 in HD – or do they?
Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing
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Bone marrow transplantation in Huntington's Disease
Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target
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2011 – a year in Huntington's disease research
Looking back at a year in Huntington's disease research – and the first year of HDBuzz
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Gene therapy meets stem cells in liver disease success
Scientists combine gene therapy and stem cells to correct a genetic liver disease. Could this combo be retooled for H
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Chinese Huntington’s Disease Network launched
Chinese Huntington’s Disease Network launched. Good news for China, good news for the global HD community
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HDAC inhibitor drug protects memory in HD mice
CBP, a gene-switching protein, protects memory in HD mice; 'histone deacetylase inhibitor' drug mimics its effects
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Turning down the volume with dantrolene helps HD mice
Dantrolene, an muscle-relaxer drug already on the market, helps HD mice by reducing cellular calcium levels
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TRACK-HD reveals changes in HD mutation carriers, empowering future trials
Follow-up data from TRACK-HD study proves that we have the tests we need to successfully run drug trials for HD
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Huntexil hits the headlines again
Huntexil makes headlines with science journal article, but nothing's changed: another trial is needed before approval
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin
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January 2026: This Month in Huntington’s Disease Research
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Phase 1 results announced for Skyhawk’s drug SKY-0515
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Huntington’s Disease Community Advocacy Helps Land Critical FDA Meeting for AMT-130
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Better Sleep, Better Function: New Study Links Sleep Quality to Clinical Outcomes in Huntington’s Disease
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