Latest News
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Lithium with a twist gets second chance for HD
Lithium gets a second chance in HD – with a new chemical delivery method, tested in Huntington’s disease mice
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High-power brain scans reveal sodium changes in HD
A new brain scanning technique reveals high sodium levels in HD brains. How might this help clinical trials?
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Mapping the neighborhood: huntingtin's new protein partners
Study of huntingtin protein's 'neighbors' reveals dozens of new drug development targets
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Does the HD mutation affect children's growth?
A small study suggests kids with the HD mutation but no symptoms have subtle differences in growth. What does it mean
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'Induced' stem cells make exciting advances
Stem cells from HD patients: becoming important tools for researchers – and now correcting the HD mutation in the lab
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ASO gene silencing reaches further, lasts longer
Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
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Phosphodiesterase inhibitors: new HD drugs entering trials soon
CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.
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Interview: CHDI's scientific team
HDBuzz interviews the top scientists from CHDI, the largest funder of Huntington's disease research in the world.
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Exercise increases cellular recycling
Exercise boosts cellular recycling in mice. Could this be why exercise is also good for HD – or even help develop dru
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The HDBuzz Prize for young science writers
Announcing the HDBuzz Prize for young science writers!
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Split Between Two Worlds: The Psychological Challenges for People at Risk of Huntington’s Disease
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Putting it in print: oral drug branaplam lowered huntingtin, but safety concerns halted development
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A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease
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Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin
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January 2026: This Month in Huntington’s Disease Research
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