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October 2025: This Month in Huntington’s Disease Research
Latest News
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HDAC inhibitor drug protects memory in HD mice
CBP, a gene-switching protein, protects memory in HD mice; 'histone deacetylase inhibitor' drug mimics its effects
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Turning down the volume with dantrolene helps HD mice
Dantrolene, an muscle-relaxer drug already on the market, helps HD mice by reducing cellular calcium levels
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TRACK-HD reveals changes in HD mutation carriers, empowering future trials
Follow-up data from TRACK-HD study proves that we have the tests we need to successfully run drug trials for HD
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Huntexil hits the headlines again
Huntexil makes headlines with science journal article, but nothing's changed: another trial is needed before approval
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New antibody reveals dangerous parts of huntingtin protein
A new antibody lets scientists identify neurons that are going to die after producing mutant huntingtin
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Safety trials add crucial piece to gene silencing jigsaw
Three trials of drugs to 'silence' the HD gene in monkeys show they hit the target safely. Human trials coming soon.
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Melatonin treatment success in HD mice
Melatonin delays disease onset and extends survival in Huntington's disease mice – could it do the same for patients?
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HD World Congress 2011: a retrospective
HDBuzz looks back at the highlights of the Huntington's disease world congress 2011 in Melbourne
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HDAC inhibitors and a possible 'blood biomarker'
HDAC inhibitors explained, plus how new HDAC-related Huntington's disease research might help us find biomarkers
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HD just got cilia
Huntington's disease just got cilia: huntingtin protein affects tiny but important hairs on cells called cilia