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January 2026: This Month in Huntington’s Disease Research
Latest News
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ASO gene silencing reaches further, lasts longer
Silencing the Huntingtin gene using ASO drugs reaches further, lasts longer and is safe. Human trial soon?
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Phosphodiesterase inhibitors: new HD drugs entering trials soon
CHDI and Pfizer announce exciting animal work and plans for a human trial with a drug targeting 'phosphodiesterases'.
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Interview: CHDI's scientific team
HDBuzz interviews the top scientists from CHDI, the largest funder of Huntington's disease research in the world.
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Exercise increases cellular recycling
Exercise boosts cellular recycling in mice. Could this be why exercise is also good for HD – or even help develop dru
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The HDBuzz Prize for young science writers
Announcing the HDBuzz Prize for young science writers!
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What's the connection between Huntington's Disease and cancer?
HD patients are less likely to get cancer, according to a study from Sweden – what does this mean?
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Closing the care gap: new guidelines for HD care
Closing the care gap: new guidelines to help every Huntington's disease patient get great care
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Stem-cell neurons make the right connections
Replacing neurons in mice with stem cells works much better than expected, suggesting that replacement therapy might
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2012 Therapeutics Conference: a retrospective
HDBuzz looks back at the 2012 Huntington's Disease Therapeutics Conference
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Mutant yeast highlights crucial CAG-reading protein
A new job for a DNA-reading protein called SPT4 – controlling the balance of mutant and healthy huntingtin protein
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
