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A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease
Latest News
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Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin
⏱️ 7 min read | A team of researchers developed a simple platform to test how toxic different types of HTT protein clumps are using a laboratory worm model. They showed that certain types of clumps are harmful to the worms, while others are not.
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Targeting oxidative stress in Huntington's Disease
Damage to cells caused by oxidative stress is part of HD – could a new targeted drug help reduce this problem?
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Of mice and men: using animal models to study Huntington's disease
Animal models of Huntington's disease: what they tell us about the disease and how can they help develop new therapie
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HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease
Recent study in fruit flies identifies a new connection between synapses and HD
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Illuminating findings in blood cells from Huntington's disease patients
Levels of the huntingtin protein can be directly measured in blood – could this be useful for gene silencing studies?
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Giving Huntington's disease the finger? Two teams report success for zinc-finger drugs in cells and mice
Success in Huntington’s disease cells and mice for zinc finger drugs that reduce production of the harmful protein
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Start here!
Huntington's disease research news. In plain language. Written by scientists. For the global HD community.
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HDBuzz Prize winner 2012: Deep brain stimulation for HD
HDBuzz Prizewinner 2012: Deep brain stimulation to treat uncontrollable movements called chorea in Huntington's disea
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Interview: Alice and Nancy Wexler
HDBuzz interviews Alice and Nancy Wexler, the sisters at the heart of the Hereditary Disease Foundation
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Video: What’s new in Huntington's disease research 2012
Watch Ed Wild's address to the European Huntington's Association on how HD research works and the most promising poss
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Shooting the messenger with single-stranded RNA gene silencing
New ‘single-stranded RNA’ gene silencing drugs could be safer & more effective to treat Huntington’s disease
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
