Latest News
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2CARE study of coenzyme Q for Huntington's disease ends in disappointment
The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?
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A starring role for astrocytes in Huntington's disease?
Brain cells called astrocytes might play a bigger role than previously thought in Huntington's disease
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HD mice provide a useful failure
Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD
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Illuminating the progression of Huntington’s disease
Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration
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Jumping genes: Huntington's disease protein invades brain transplants
A long-term study of the brains of HD patients who received grafts of fetal tissue reveals a surprising result
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The brain in Huntington's disease: greater than the sum of its parts?
An important new study asks the question: what parts of the brain might need most help in HD?
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NUB1: enhancing clearance to decrease mutant huntingtin
NUB1 increases mutant huntingtin removal from cells, reducing the toxic effects of HD in fruit flies
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Could HD be caused by amino acid deficiency?
Does a specific amino acid deficiency contribute to the development of HD?
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Raptor announces results of cysteamine trial for Huntington's disease
Raptor Pharmaceuticals announces intermediate results from a long-term study of cysteamine in Huntington's disease
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Sleep, cilia and HD
New studies shed some light on the function of sleep in animals, with interesting implications for HD research
HDBuzz Trial Tracker
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Additional insights from Phase 2 study results and update on plans for Phase 3 trial for votoplam
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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Split Between Two Worlds: The Psychological Challenges for People at Risk of Huntington’s Disease
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Putting it in print: oral drug branaplam lowered huntingtin, but safety concerns halted development
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A hitch in the stitch reveals why DNA sequence patterns matter in Huntington’s disease
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Worms to the Rescue: Separating the Good, the Bad, and the Clumpy Huntingtin
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January 2026: This Month in Huntington’s Disease Research
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