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First participants dosed in new POINT-HD huntingtin-lowering trial
Latest News
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A road less traveled: how making less huntingtin can alter somatic instability and may delay symptoms
CAG repeats can get longer over time as the HD gene is used, like the growing potholes and cracks in an old road. New research finds that blocking cells from using their HTT gene slows this wear and tear, which might slow the onset of symptoms in HD.
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EuroBuzz 2014: day one
Highlights from the opening day of the 2014 European Huntington's Disease network in Barcelona, Spain
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Going toe-to-toe with tau: new insights into the chemical basis of Huntington’s disease
Does tau protein – which causes problems in other neurodegenerative diseases – contribute to Huntington's disease?
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New results bring BDNF therapies into focus
Some unexpected findings suggest new ways to aim at an old target in HD
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2CARE study of coenzyme Q for Huntington's disease ends in disappointment
The largest ever HD drug trial, testing coenzyme Q10, is halted for 'futility'. What does that mean for HD research?
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A starring role for astrocytes in Huntington's disease?
Brain cells called astrocytes might play a bigger role than previously thought in Huntington's disease
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HD mice provide a useful failure
Can drug trials that fail be helpful? A HD mouse study provides solid evidence of an approach that doesn't help HD
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Illuminating the progression of Huntington’s disease
Researchers have used mice with glowing brain cells to decipher the first steps of neurodegeneration
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Jumping genes: Huntington's disease protein invades brain transplants
A long-term study of the brains of HD patients who received grafts of fetal tissue reveals a surprising result
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The brain in Huntington's disease: greater than the sum of its parts?
An important new study asks the question: what parts of the brain might need most help in HD?
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NUB1: enhancing clearance to decrease mutant huntingtin
NUB1 increases mutant huntingtin removal from cells, reducing the toxic effects of HD in fruit flies
