Latest News
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Enemy at the gates – huntingtin disrupts nuclear transport
Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.
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FDA approves a new drug for symptoms of Huntington's disease
Deutetrabenazine becomes the first new drug in a decade licensed by the FDA for symptoms of Huntington's disease
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Sheep leading the flock: metabolism and biomarkers in HD
Sheep can help us to identify HD biomarkers and recognize metabolic changes that occur before symptoms develop.
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Weeding out the truth: can cannabis improve Huntington’s?
What can individual experiences with cannabis tell us about Huntington's disease?
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Huntingtin grabs a hammer: DNA repair in HD
Huntingtin helps fix damaged DNA, a recent study suggests, under the direction of a gene repair protein called ATM.
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The benefits of migration, highlighted in Huntington's disease
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
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Treasure your exceptions – using outliers to understand Huntington's disease onset and progression
A new study provides the framework for finding factors that affect the onset and progression of HD
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A powerful message: does a toxic RNA message molecule cause harm in Huntington's disease?
What if some problems in HD were due to something other than a harmful protein?
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Pfizer Amaryllis trial ends in disappointment: no improvement in Huntington's disease symptoms
Pfizer announces the 'Amaryllis' trial of a PDE-10 inhibitor drug failed to improve symptoms of HD
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Important advances in next generation genome editing tools for Huntington's Disease
Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials
HDBuzz Trial Tracker
Sites for Phase 3 trial for votoplam, INVEST-HD, now open. Updates on recruitment and first dosing imminent.
Progress update for NCT06585449 – A Study to Evaluate ALN-HTT02
Updates from the ongoing placebo-controlled Phase 2/3 FALCON-HD trial
Previously featured
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March 2026: This Month in Huntington’s Disease Research
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Two Heads Are Better Than One: Combined Physical and Music Therapy for Late-Stage Huntington’s Disease
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A Guest Perspective for Gratitude Day: Why Huntington’s Disease May Be Neuroscience’s Best Investment
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The Girl at the End of the World: A Gratitude Day Reflection on the Place that Built Our Science
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Turning down mismatch repair genes slows Huntington’s repeat growth in human neurons
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