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First participants dosed in new POINT-HD huntingtin-lowering trial
Latest News
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A road less traveled: how making less huntingtin can alter somatic instability and may delay symptoms
CAG repeats can get longer over time as the HD gene is used, like the growing potholes and cracks in an old road. New research finds that blocking cells from using their HTT gene slows this wear and tear, which might slow the onset of symptoms in HD.
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Liftoff: First humans treated with gene silencing drugs for HD!
Major Announcement: First HD patients treated with gene silencing drugs
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HDBuzz primer: Clinical trial designs and phases
HDBuzz untangles hope from hype in clinical trial announcements
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A Few Bad Seeds: Using Brain Fluid to Grow Clumps in Brain Cells
HD brain fluid makes brain cells grow clumps.
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New tool to measure outcomes in Huntington’s Disease clinical trials
A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain
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Huge study reveals new 'genetic modifiers' of Huntington's disease
GeM-HD identifies the first solid leads in the hunt for genetic variations that affect Huntington's disease onset
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Would ewe believe it? GM1, sheep and Huntington's disease
HD researchers and sheep farmers are collaborating on a brain fat called GM1, but a clinical trial is a long way off
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Switching it up: variety in the HD gene affects symptom onset
Variety in the HD gene’s on switch affects when symptoms arise.
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Measuring harmful huntingtin protein in the brain’s bath water
How will we know whether HD-lowering treatments are working? New advancements in the detection of mutant huntingtin.
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A faulty filter? Blood vessel changes in Huntington's disease
New research reveals blood vessel changes that could contribute to problem in HD
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Lighting the way: A new biomarker for Huntington’s disease
A new biomarker reveals brain changes in early Huntington's disease.
