Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.
The third and final day of the 2016 Huntington's Disease Therapeutics Conference brings updates on cell replacement therapies including stem cells; and new ways to assess and model the progression of HD to help understand it and run crucial clinical trials.
Scientists can now reprogram human skin cells to make working cells that resemble 'medium spiny neurons', the type of brain cell that is most affected early in Huntington's disease. We're still a long way off from being able to replace the brain cells that are being lost in HD, but this research is an important step down that path, and is a great tool to study HD.
Huntington's disease is caused by the malfunctioning and early death of brain cells. Replacing those dead and dying cells with stem cells has long been a goal of some HD scientists. A new study investigates the long-term health of some of the earliest cell transplants into HD patient brains — and finds a surprising result.
Watch the video of Ed Wild's address to the European Huntington's Association annual meeting in September 2012, summarizing how therapies research works and explaining the most exciting ways researchers are trying to study and treat HD.
Jeff Carroll and Ed Wild present EuroBuzz episode 2 - bringing the European HD Network Meeting direct to you, in plain language. Watch online!
Our second daily report from the European Huntington’s Disease Network 2012 Meeting in Stockholm. Video of both EuroBuzz evening sessions will be available to watch on HDBuzz.net next week.
Our first daily report from the European Huntington’s Disease Network Meeting in Stockholm. Follow us live for the second day on Twitter or Facebook at HDBuzzFeed. Video of the day's live Euro Buzz session - with news, interviews and features - will be available to watch on HDBuzz.net soon.
Stem cells are a source of great excitement for patients suffering from illnesses caused by the death of cells in the body - like Huntington's disease. But the devil is in the details, and actually using these powerful cells to help HD patients is a complex problem. Now, two new studies have advanced stem cells as a tool for researchers, and prove that it is possible - in cells in a dish - to correct the mutation that causes HD.
New work suggests that neurons made from stem cells can replace adult neurons better than we thought – at least in mice whose brains have been injured with a toxin. How likely is this to help HD patients – is cell replacement possible in a more chronic condition?