New experiments clarify the role of SIRT1 in HD - or do they?

New experiments clarify the role of SIRT1 in HD - or do they?

Work from multiple labs suggests activating a protein called SIRT1 might help HD, but the picture is still confusing

Dr Jeff CarrollJanuary 12, 2012

Bone marrow transplantation in Huntington's Disease

Bone marrow transplantation in Huntington's Disease

Bone marrow transplant protects HD mice from some symptoms, suggesting the immune system may be an important target

Dr Tony HannanJanuary 04, 2012

2011 - a year in Huntington's disease research

2011 - a year in Huntington's disease research

Looking back at a year in Huntington's disease research - and the first year of HDBuzz

Dr Ed WildDecember 31, 2011

Gene therapy meets stem cells in liver disease success

Gene therapy meets stem cells in liver disease success

Scientists combine gene therapy and stem cells to correct a genetic liver disease. Could this combo be retooled for H

Dr Michael OrthDecember 26, 2011

Chinese Huntington’s Disease Network launched

Chinese Huntington’s Disease Network launched

Chinese Huntington’s Disease Network launched. Good news for China, good news for the global HD community

Dr Jeff CarrollDecember 21, 2011

HDAC inhibitor drug protects memory in HD mice

HDAC inhibitor drug protects memory in HD mice

CBP, a gene-switching protein, protects memory in HD mice; 'histone deacetylase inhibitor' drug mimics its effects

Dr Ed WildDecember 13, 2011

Turning down the volume with dantrolene helps HD mice

Turning down the volume with dantrolene helps HD mice

Dantrolene, an muscle-relaxer drug already on the market, helps HD mice by reducing cellular calcium levels

Dr Jeff CarrollDecember 08, 2011

TRACK-HD reveals changes in HD mutation carriers, empowering future trials

TRACK-HD reveals changes in HD mutation carriers, empowering future trials

Follow-up data from TRACK-HD study proves that we have the tests we need to successfully run drug trials for HD

Prof Anne RosserDecember 05, 2011

Huntexil hits the headlines again

Huntexil hits the headlines again

Huntexil makes headlines with science journal article, but nothing's changed: another trial is needed before approval

Dr Ed WildNovember 22, 2011

New antibody reveals dangerous parts of huntingtin protein

New antibody reveals dangerous parts of huntingtin protein

A new antibody lets scientists identify neurons that are going to die after producing mutant huntingtin

Dr Jeff CarrollNovember 17, 2011

Safety trials add crucial piece to gene silencing jigsaw

Safety trials add crucial piece to gene silencing jigsaw

Three trials of drugs to 'silence' the HD gene in monkeys show they hit the target safely. Human trials coming soon.

Dr Ed WildNovember 14, 2011