Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

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Articles with the topic: buzz-prize

NUB1: enhancing clearance to decrease mutant huntingtin

NUB1: enhancing clearance to decrease mutant huntingtin

Lakshini Mendis on May 12, 2014

Huntington’s disease is caused by the accumulation of the toxic mutant huntingtin (mHTT) protein. This means that decreasing levels of mHTT, by boosting its breakdown, could be therapeutically beneficial. Palacino and colleagues have identified a possible contender for this role: negative regulator of ubiquitin-like protein 1, better known as NUB1.

Joint HDBuzz Prizewinner: Yeast studies suggest a new way to protect cells from 'oxidative damage'

Joint HDBuzz Prizewinner: Yeast studies suggest a new way to protect cells from 'oxidative damage'

Leora Fox on February 05, 2014

Many types of stresses occur within cells that have the HD gene, and examining how simple organisms cope can help scientists define new targets for HD drugs. A new study examines yeast to determine which proteins can protect these cells from damage and death, uncovering a protective antioxidant and a related drug.

Joint HDBuzz Prizewinner: Pennies for your neurons — copper’s bad influence on Huntington’s disease

Joint HDBuzz Prizewinner: Pennies for your neurons — copper’s bad influence on Huntington’s disease

Terry Jo Bichell on January 30, 2014

Copper, the metal, may play a role in worsening the symptoms of Huntington’s disease. Bing Zhou and his team looked for connections between HD and the amount of copper in neurons. They report that reducing copper in neurons or keeping it from binding to the HD protein improves symptoms.

The 2013 HDBuzz Prize for Young Science Writers

The 2013 HDBuzz Prize for Young Science Writers

Dr Ed Wild on September 02, 2013

We’re pleased to announce the 2013 HDBuzz Prize, an opportunity for early-career Huntington’s disease researchers to get involved in communicating HD science to the global community, see their work published here and win US$500 in Amazon vouchers!

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

HDBuzz Prize runner-up 2012: Fruit flies, faulty connections and Huntington's disease

Dr Tamara Maiuri on November 16, 2012

Synapses, the connections between neurons, may turn out to be a good target for Huntington's disease therapies. Recent research has identified a new piece of the puzzle regarding synapses and HD-and a new target to aim for.

HDBuzz Prize winner 2012: Deep brain stimulation for HD

HDBuzz Prize winner 2012: Deep brain stimulation for HD

Melissa Christianson on October 29, 2012

Deep brain stimulation - a procedure in which miniature electrodes that release pulses of electricity are implanted into the brain - sounds like something out of a scary science fiction movie. However, this sci-fi-like treatment may prove useful for reducing symptoms of uncontrollable movement known as chorea in patients with HD.

The HDBuzz Prize for young science writers

The HDBuzz Prize for young science writers

Dr Ed Wild on May 03, 2012

We're pleased to announce the HDBuzz prize, an opportunity for early-career Huntington's disease researchers to get involved in communicating HD science to the global community, see their work published here and win real human money!