Two recent studies show how a cellular border control system goes wrong in HD, opening new avenues for HD research.
Is HD a developmental disease? HD stops neurons migrating in developing brain, but maybe we can get them going again
A surprising new mouse study suggests the mutant HD gene may do some of its damage during embryonic development
Harmful misfolded huntingtin can travel between brain cells via messenger particles called exosomes
An existing drug could give a boost to HD brain cells – but it may need more testing before it’s back in the clinic
Fingolimod, a drug used in multiple sclerosis, prevents memory problems in HD mice. Would it work in patients?
A better tool for HD trials! New research shows innovative way to measure mutant Huntingtin outside the brain
New research reveals blood vessel changes that could contribute to problem in HD
Researchers use a new technique in an HD mouse to uncover a gene, Gpx6, that is protective to vulnerable neurons.