Huntington’s disease research news. In plain language. Written by scientists. For the global HD community.

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Articles with the topic: huntexil

Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease

Sorry folks, the PRIDE-HD trial did NOT show that Pridopidine slows the progression of Huntington's disease

Dr Jeff Carroll on September 30, 2016

A recent press release from Teva Pharmaceuticals has the HD community excited, claiming "Pridopidine Demonstrates Slowing of Progression of Huntington Disease in PRIDE-HD Study". What's pridopidine, and what can we really say about HD progression in patients treated with it?

No surprises in published results from HART study of Huntexil for Huntington's disease

No surprises in published results from HART study of Huntexil for Huntington's disease

Dr Ed Wild on March 12, 2013

A new paper in the journal Movement Disorders reports the findings of the HART study of pridopidine, also known as Huntexil - a new drug aimed at improving movements in people with Huntington's disease. Unfortunately this publication doesn't change much - a new, larger trial is still needed before we will know whether Huntexil works.

Huntexil hits the headlines again

Huntexil hits the headlines again

Dr Ed Wild on November 22, 2011

The results of the MermaiHD trial of Huntexil for movement problems in HD have been published in the scientific journal Lancet Neurology. Despite conflicting media reports, this doesn't change the need for a further trial before Huntexil can be approved for use in patients.

Huntexil update: EMA asks for further trial

Huntexil update: EMA asks for further trial

Dr Ed Wild on June 06, 2011

In April, the American drug regulator told NeuroSearch it would need a further large clinical trial before its Huntington's disease symptom-control drug Huntexil would be licensed. Now the European regulator, the EMA, has said the same for European licensing.

Improving Huntington's disease clinical trial recruitment through patient and family education

Improving Huntington's disease clinical trial recruitment through patient and family education

Dr Jeff Carroll on May 12, 2011

Trials of new treatments for Huntington's disease are happening, but proving whether a drug works requires lots of suitable volunteers. Surprisingly, finding enough volunteers is often difficult. Now a group of HD professionals has shown that education and outreach to patients in the community works well for boosting recruitment.

FDA: further trial needed for Huntexil approval in HD

FDA: further trial needed for Huntexil approval in HD

Dr Jeff Carroll on April 04, 2011

NeuroSearch, the developer of experimental Huntington's disease drug Huntexil, has reported on their meeting with the FDA. The FDA requires that another trial be conducted before Huntexil could be approved in the US.

Huntexil for symptoms of Huntington's disease: where are we now?

Huntexil for symptoms of Huntington's disease: where are we now?

Dr Ed Wild on November 16, 2010

2010 was a big year for the small Danish pharmacology company NeuroSearch and its experimental drug, Huntexil, which aims to improve the movements and coordination of people with HD symptoms. What have NeuroSearch's two clinical trials - MermaiHD in Europe and HART in the USA - told us about the possible benefits of Huntexil - and what is likely to happen next?